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Lionloans.com Quick Cash Bad Credit And No Credit Ok

January 15, 2018

Internet Services

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You will find more than ten thousand paycheck lenders in the United States by yourself, and many more internationally. Utilize this truth in your favor. Engage in competitors off from the other person for much better bargains. Find out who has the best offer, and try to take advantage of this details as leveraging over someone in your area.
In no way submit a cash advance program just before do you know what prices you may be billed for that personal loan you are hoping to acquire. A lot of cash advance firms can tell you to fill in kinds before you are aware of the price, but which will just make you accountable for it even unless you acknowledge.
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When you are in the significant fiscal combine, try out borrowing the cash you will need from the comparable, or one of many options just before, you think of acquiring a payday advance. Ever since the curiosity on these kind of financial loans are so ridiculously substantial, they should basically be viewed as a last option.
Normally, payday loans are quick, and simple to acquire. They may be expensive. To have the dollars you will need at a cheaper or no expense, you should think of wondering some of your loved ones, or buddies to borrow the amount of money you need. As a result, you can save some cash, and have access to the resources you require.
When you are possessing problems repaying your payday loan, allow the financial institution know as soon as possible. These loan companies are used to this case. They are able to assist you to definitely build a continuous settlement solution. If, instead, you ignore the loan provider, you will discover yourself in collections before very long.
Usually do not permit private connections get when it comes to your opinion in terms of payday loans. If a loved one is rejected a pay day loan, will not say yes to get on in their account. This may cause you accountable if he chooses that he or she does not wish to pay it rear.
Before finalizing your payday advance, read every one of the small print in the arrangement. Payday loans could have a lots of legal words hidden in them, and in some cases that legal words is used to mask hidden charges, great-valued past due fees along with other things which can destroy your wallet. Before signing, be smart and know exactly what you are actually signing.
Look into each of the charges that come along with payday loans. Using this method you probably know how a lot you will be in fact having to pay to obtain money. There are numerous interest rules to protect buyers. Pay day loan firms travel these by, charging a long list of “costs.” This may add more considerably to the price of borrowing funds. This might enable you to choose regardless of if the personal loan is totally essential.
You are going to receive an email indicating, you have been authorized for the cash advance. Once you receive that e-mail, be sure you go over the problems in the financial loan well before agreeing to it. The circumstances may have changed following, they investigated your credit report. Exercise caution when rejecting the financing. Many times, you can expect to be unable to reapply for about 1 month.
Look at simply how much you honestly have to have the cash that you will be considering borrowing. When it is a thing that could hold out till you have the funds to acquire, place it off. You will probably realize that pay day loans usually are not an inexpensive option to invest in a large Television set for a football activity. Restriction your borrowing with these loan providers to unexpected emergency circumstances.
It is recommended to not use payday cash loans to cover luxury goods, for example TV’s or getaways. They may be best employed in situations where it comes with an unexpected emergency, or possibly a costs you cannot pay promptly. Should you need money for high end products, it is better to consider a loan through your financial institution, or even a very low-curiosity bank card. The attention charged on this kind of credit history will always be less than a cash advance.
Exactly like other things being a consumer, you have to do your homework and shop around for the best prospects in payday cash loans. Be sure you know all the information all around the personal loan, and that you are becoming the very best costs, conditions and also other situations for your personal distinct financial predicament.

Speak To A Specialist To Get Help With Your Concrete Concerns

January 8, 2018

Miscellaneous

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Concrete is oftentimes utilized in organizations for the floors due to its longevity as well as simply because it may be made to appear precisely how they’ll need. Although this flooring option is actually great for organizations since it will hold up to a great deal, over time it could need to be restored. Whether or not the company owner needs concrete leveling winnipeg or another kind of repair, it is a good idea for them to contact an expert for assistance.

Experts will be in the position to get the work carried out as quickly as possible to decrease virtually any interruption to the company. They currently have each of the tools required to be able to perform the job and also they’ll have the knowledge required in order to make sure the flooring is going to look fantastic when they may be done. They’re going to be in a position to complete virtually any repairs the company may have to have as fast as possible and make sure the brand-new flooring looks the same as the older flooring in scenarios where they do not need to repair the whole floor. This way, shoppers can’t tell repairs have been done.

If perhaps you’re in need of concrete repair winnipeg, make sure you go to the website to be able to learn far more with regards to how a specialist could help. Make contact with them now to enable them to let you know precisely what has to be carried out for your floorings.

It Was the Toilet Replacement That Did a Job on My Back

December 14, 2017

Uncategorized

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I was doing a little renovating at our house. Just the stuff I could do. I painted the bathroom and put down a peel-and-stick plank floor that looks great. I pulled the toilet up before I did the job. We were replacing it. When I went to seat the new toilet over the flange in the floor, I hurt my back. I pulled something. I should have used a toilet jack. Yes, there is such a thing. When I told the Valley Village chiropractors I went to, they seemed to get a kick out of how I hurt my back.

I am not sure what I did. I was holding the toilet up in the air over the flange while my wife was on the floor looking to make sure I had it lined up. I was getting a bit fatigued getting it into perfect position before placing it on the floor. Those wax seals are only good for one go. Maybe it wasn’t holding the heavy toilet up in the air.Read More »

6 Alarming Signs of Heart Disease

November 1, 2017

Heart Disease Article

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Modern lifestyle and day to day stress has made heart diseases one of the leading health risk people face today. The heart disease comprises of-

  • Arrhythmias
  • Angina
  • Coronary artery disease (CAD)
  • Heart failure
  • Infections related to heart

Most people think that the symptoms of heart disease are obvious- a sudden, crushing feeling in the chest and shooting pains down the arm followed by a fall on the floor. But you may develop heart disease without even knowing it, as some heart symptoms don’t even happen in your chest.

Knowing the hidden signs of heart disease is crucial to get early treatment and prevent more serious health issues. Thus, we have put together this quick guide to six of the most alarming hidden signs with their medical reasons which signifies that all is not well with your ticker.

  1. Light Headedness and dizziness

Random dizziness or feeling faint can signpost the problems like an irregular heart rhythm or even a heart attack

Medical Reason– Drop in Blood pressure or an abnormal heart rate can cause reduced blood supply to brain.

  1. Reduced tolerance to exercise

Struggling with physical activities that you previously found easy could be an indication that your heart is struggling.

Medical Reason– When your heart becomes unhealthy, it is less effective at pumping oxygen-rich blood to your muscles, and so physical activity becomes harder.

  1. Spontaneous sweating

Perspiring at random moments, like while sitting or relaxing, could be an indication of heart disease.

Medical Reason– Heart problem can result in over-activation of the sympathetic nervous system which can make you sweat at unexpected times.

  1. Memory Loss

Memory loss and befuddled thinking is an understated sign, might first be noticed by friends or family before you do.

Medical Reason– Heart problem may cause restricted blood flow to the brain leading to injury to the brain cells resulting in memory loss.

  1. Swelling in feet

Your feet might feel sore and visibly swollen with no obvious explanation. This may go together with sudden weight gain.

Medical Reason– If your heart is not pumping well, the blood returning to the heart gets backed up causing the fluid to accumulate in the tissues of the legs, ankles and feet.

  1. Non-chest pain

Chest pain is not the only sign of Heart problem. The pain can also be felt in shoulders, arms, elbows, jaw or neck.

Medical Reason-It is termed as referred pain, i.e. a person feels pain in an area away from the actual source of the pain. This can occur when strong pain stimulus running along nerves overpower nearby nerves, causing pain to be felt elsewhere.

Prevention remains the best cure whether you have symptoms or not. So, follow simple steps like no smoking, eat good, do exercise, stay healthy and your heart will remain healthy.

 

Supplements That Are Good for Heart Health

November 1, 2017

Heart Disease Article

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It is not a secret that vitamins are essential for our overall health. To get the required amount of vitamins it is important to maintain a well-balanced diet. However, nutrients we consume from our daily diet may not be sufficient and our body may need additional supplementation to maintain its proper functioning. Supplements are not intended to treat diseases, but are of value to supply body with enough essential nutrients and vitamins to improve health when taken properly under doctor’s control.

Want to keep your heart healthy and reduce the risk for heart disease? Then supplement your body with these nutrients and pills that are good for your heart health.

Aspirin – an anti-inflammatory drug that helps thin the blood, making it more difficult for the body to form clots. One 80 mg aspirin tablet daily should be taken by anyone who is over 50 and has such risk factors as a family history of heart attack, high total cholesterol level, sedentary lifestyle, previous cardiac event or hypertension.

Omega-3 fatty acid is helpful in balancing blood lipids. Fish oil helps prevent heart attacks because it slows down the build-up of plaques in the arteries, promotes blood vessel dilation, reduces stiffness and improves vascular function. A serving of oily fish like mackerel, salmon and tuna or 1,000 mg in capsule form daily is helpful for people with high triglycerides and those at risk of heart disease.

Vitamin D is essential because it helps the body to properly absorb all the beneficial aspects of zinc, iron, calcium, magnesium and phosphate. Doctors recommend taking this supplement for treating high cholesterol and hypertension – issues that affect blood vessels and overall health. Dairy products, fish oils, beef liver, egg yolks, regular exposure to sunlight or 400 to 800 IU a day will help maintain consistent levels of this vitamin.

Coenzyme Q 10 helps the body generate energy via aerobic cellular respiration and is known to improve muscle function as well as increase heart contractility. It also fights free radicals, promotes arterial health and helps maintain healthy blood pressure and cholesterol levels. 100-200 mg a day is especially beneficial for older individuals, patients with heart failure, hypercholesterolemia and those taking statins.

Niacin or vitamin B3 is naturally involved in carbohydrate and lipid metabolism. It supports healthy cholesterol levels and is a potent vasodilator. It is effective at high doses, which must be taken under doctor’s supervision like any other vitamin supplement for heart, and is recommended when there is a genetic predisposition to heart disease, low HDL levels, atherosclerosis issues and previously suffered cardiac arrest.

Chocolate Can Do Wonders to Reduce Heart Disease

November 1, 2017

Heart Disease Article

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What are the possible factors which could help reduce heart disease? Do you know? Most people do not have any idea that the common things we use in our daily life can also do heart disease prevention. Heart disease is one of the diseases which can endanger person’s life all of a sudden as a result of heart attack or heart failure. There are hundreds of reasons for a sudden heart failure in people no matter what age they are of.

Chocolate!

One of the most commonly used things is the delicious chocolate used by every other human being at least once in a month in one form or another. If people know about the importance of this important ingredient they would definitely increase its use to do heart problem prevention in their lives. Doctors recommend people to do chocolate consumption on daily basis in any form to prevent cardiac diseases. Dark Chocolate is significantly recommended since it contains large amount of nutrients which are good for a person’s health. It contains antioxidants which help reduce heart diseases. It has abundance of fiber, magnesium, iron and potassium which have the ability of heart disease prevention. Knowing about the heart disease prevention diet is very important these days, since the heart disease is widespread in almost every country of the world.

Chocolate maintains a good blood flow

One of the most important reasons of using chocolate for heart problem prevention is its ability to smooth en the blood flow in a person’s body. It not only smooth ens the blood flow but also lowers the blood pressure which becomes the main reason for the heart attack in most of the cases. Cocoa has bio active elements in it which accelerates yet smooth ens the blood flow in the arteries and ultimately results in lowering the blood pressure. The anti-oxidation elements in Cocoa restricts the cholesterol to get accumulated in the arteries which becomes another big reason of a heart attack. In this modern world, cocoa is considered as a medicine to ensure better cardiovascular health. It does not only have a magnificent taste but it has large healthy benefits for a human body. People should use the diet which reduces heart disease risk and contribute to heart disease prevention and treatment. People should follow heart disease prevention tips to avoid cardiovascular mishaps in their body.

Other ways to reduce

The smooth functioning of a human body is essential for a health life and this article will tell you about the heart disease prevention to some extent. The smooth blood circulation in the body is essential for a smooth functioning of heart which can only be made possible through using diet.

Reduce heart disease through intake of healthy foods

Over weight of body do not result to reduce heart problem but oppositely is complementary to cause it. Mostly people with more weight have to experience the heart disease which can become deathly if not taken care of properly at appropriate time through right heart prevention tips. In most of the cases, the doctors’ recommendations include the reduction of weight in the heart disease treatment. They pressurizes the patient to reduce his weight to help burn the calories and reduce the cholesterol level which is often the main reason of cardiovascular diseases.
• The patients with heart diseases should take healthy diet including rich amount of whole grains which is mostly present in brown rice and bread.
• Olive Oil should be made a significant ingredient of the food.
• He should eat sea food on regular basis instead of red meat which is not so healthy for any human body if consumed in abundance.
• There are many brands available which offers low fat or fat-free dairy products. To prevent the health disease one should make the low fat eatables an important food on regular basis.
• Sodium is not good since it increases the blood pressure. That’s why whatever that has rich sodium in it should be avoided.
• Fruits should be taken in abundance.
• Fried food should be avoided and preferably grilled or steamed food should be taken in heart prevention diet.

Exercise is best to have a healthy life!

Not only healthy foods but there are many exercises which a person can do to help. Doing exercise on daily basis, keeping your body fit and used to of a stressful activity can help a lot in dealing with the cardiac diseases and coping with them on a long term basis. What is heart made up of? It is made up of muscles which need to stretch and exercise all the time. When a person exercises, his heart starts pumping the blood all over the body and starts functioning with greater efficiency. This will keep the heart’s life to live longer. Exercise on regular basis is very important for a human body for burning calories and decreasing the amount of accumulated cholesterol. It is common to know that exercise keeps the heart flexible in pumping blood out and keeps the blood pressure normal. Doctors recommend that every person should exercise for at least 30 minutes daily to keep the body fit and healthy. Yoga and jogging at an appropriate rate of running is considered good for the heart disease prevention as well as treatment. The healthy heart burn off your stress and makes you sleep better which ultimately results in a healthy and fit life. These heart prevention tips should be adopted in his/ her life to live longer.

Mitral Valve Prolapse: Get The Facts Before Treating – It Could Be Dysautonomia

November 1, 2017

Heart Disease Article

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Many people are diagnosed each year with mitral valve prolapse, which indicates that one or both of the mitral valves aren’t opening and shutting correctly as blood is pumped from the top part of the heart to the bottom part where it then goes out to the rest of the body. This diagnosis infers that the valve is prolapsed due to a structural problem with the valve itself, requiring surgical correction or replacement to correct the problem.

People usually go to the doctor with symptoms like lightheadedness or fainting (syncope), racing heart when standing (tachycardia), gastrointestinal issues, general fatigue, low blood pressure, numbness, brain fog, etc., and when tests indicate that blood flow through the heart isn’t right, or it looks like the valves aren’t opening and shutting right, then the diagnosis is often mitral valve prolapse. Then for some reason, this diagnosis infers that there is something structurally wrong with the valve. What’s important to keep in mind about this diagnosis is that the dysfunction of the valve may not be a structural defect that requires surgery–it may actually be a dysfunction of the autonomic nervous system or dysautonomia that is actually behind the valve not operating properly.

As you might guess, mitral valve prolapse often has symptoms similar to dysautonomia symptoms. And when they can’t put their finger on exactly what is causing the valve dysfunction or the group of symptoms, they call it MVP syndrome–which is actually dysautonomia when you get down to the details. Fortunately, many forms of dysautonomia can be treated and effectively with a variety of natural treatment options including nutritional supplementation, exercise, maintaining proper water and electrolyte balance, and other things that don’t require surgery.

Granted, in some cases there is a structural defect or problem with the valve that does require surgery to correct. But if there’s any doubt at all about that, it can be more than worth your while to seek the opinion of an autonomic disorder specialist or dysautonomia doctor and at least let them run a few tests, and certainly before undergoing surgery. And the best places to do that is to Google something like dysautonomia doctor or dysautonomia treatment center. Even if there isn’t one locally where you are, it can be worth it to travel to a top-rated clinic and get some definitive answers before you start other treatment protocols. It is far better to be as clear as possible about what is going on and then begin treatment than to start treatments when you’re not sure.

How Stress Drives Up Cholesterol, BP and Belly Fat – What to Do About It – It’s Not Drugs

November 1, 2017

Heart Disease Article

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If you have elevated cholesterol, high blood pressure and or belly fat you need to read this article. It will help you understand why taking medication is not the only answer or choice to reducing cholesterol. I will share with you a general understanding of how stress drives up cholesterol, blood pressure and belly fat.

Elevated cholesterol is a risk factor for cardiovascular disease and a big concern for many. The first question to ask is where does cholesterol come from? The research shows, 15-30% of the total blood cholesterol comes from your diet depending on what you eat. Over the last 25 years or so there has been a huge public awareness campaign for people to stop eating cholesterol. So we see food packages with a “no cholesterol” label.

And here is a key finding… many have actually reduced their cholesterol intake yet they may still have elevated cholesterol in their blood. How is this happening?

Your body makes cholesterol in the liver and this may account for some 70-85% of the total cholesterol in you blood.

So even if you eat zero cholesterol your body would make all it needs in the liver.

A smart question to ask is why is my body making cholesterol? What is stimulating it to produce it and an even better question would be how can I slow it down? What is becoming very clear in the research is that one of the strongest stimuli on the liver to produce cholesterol is… insulin! Yes that’s the hormone involved in blood sugar management.

Insulin is a very powerful stimulus that tells the body to store energy and produce cholesterol. In the liver it turns on enzymes that produce cholesterol. Insulin also stimulates the liver to make more LDL the “bad” cholesterol.

Now you are probable asking, what makes my insulin levels go up? Great question. One of the biggest components is your diet and specifically your intake of the sugar spiking foods. We call these the High Glycemic foods. It can also be the excessive intake of carbohydrates which as a society we take in way to many.

Nutrient insufficiencies can also contribute to “insulin resistance”. This means the insulin receptors that help bring down blood sugar don’t work quite right so the body compensates and produces more insulin to get the job done, to drive the sugar into the cells.

There are also other factors at play that alter you physiology to increase insulin.

One very key player is lack of sleep. Reducing your sleep from 8 hours to just 6 hours a night for 7 days can greatly increase your insulin production. (It will also increase hormones that make you eat more as well reduce your satiety so you don’t feel full and keep eating.)

And finally the elevated stress hormone, which is called cortisol, also drives up insulin in turn driving up cholesterol production. Cortisol elevates blood sugar and insulin reduces it thus they work in opposition. Chronic stress drives up insulin, which in turn drives up cholesterol production. It is also interesting to note that lack of sleep also greatly drives up cortisol levels and feeds forward this cycle. Cortisol also directly acts directly on the liver to increase cholesterol production.

The story doesn’t stop here. It has been know for a long time that elevated blood pressure is part of the “ticking time bomb” of cardiovascular disease. Often many have elevated cholesterol and elevated blood pressure and maybe even belly fat at the same time. Insulin also working through multiple mechanisms contributes to “vascular inflammation” which is what drives up blood pressure (BP). And chronic stress also causes elevated blood pressure directly.

Earlier it was stated that insulin promotes storage of fat. It does this everywhere on the body including the belly area. The fat tissue around you organs is unique in that it has high levels of cortisol receptors. What this means to you is…

when you are chronically stressed, the fat cell are continually getting the signal to “store fat”.

The external “symptom” is that you gain belly fat. It is a sign that your physiology is out of balance and has been for a while. Simply cutting calories is not the answer to reducing belly fat.

It is vital to understand that belly fat sits in you not on you. It sits deep within your abdominal area around your organs where it causes damage. It is the most dangerous type of fat.

There is a condition called Metabolic Syndrome which to simplify we could say is kind of like “pre-diabetes”. Some of the “symptoms” include elevated blood pressure and or cholesterol, and or elevated LDL and low HDL and belly fat. Can you see how these pieces of the puzzle work together to give or take away your health?

Elevated cholesterol is not your problem.

Your out of balance physiology which is driving up cholesterol production is. And that’s most likely due to your lifestyle. You have complete control over these factors! As a matter of fact the major governing bodies that recommend treatment to doctors recommend diet and lifestyle before medications!

Now, you could use medications (statin drugs) to bring down your cholesterol. And they can do that but they do have some negative effect associated with them namely muscle pain and fatigue. Or you could work “upstream” and take actions which give you direct control and which directly target the root cause of your elevated cholesterol (and other risk factors!). What’s your choice?

Some key solutions include: Improving the amount of your sleep to the recommended eight hours per night, focus on reducing stress in all the different areas of your life (workplace, home life, life purpose, mission, direction, reducing sources of inflammation, financial stress, etc) that is the key area of my writings. See website Stress Reduction Stress Relief to get more free training videos.

And also key is reducing your intake of high glycemic carbohydrates, reducing intake of “liquid candy” and boosting your diet with key nutrients to overcome any shortfalls (multi vitamin-mineral).

Increasing both soluble and insoluble fibers will help to stabilize blood sugar, reduce insulin as well as bind cholesterol before it enters your blood which all bring cholesterol down.

I can also strongly recommend and encourage you to move more. Can you move more for fun, joy purpose and socialization? Of course you can. Exercise helps tire one out so we sleep better, it works better than any medication to improve insulin resistance and lower insulin levels, it help “burn” stress and fat and it gives our bodies muscle tone which is sexy! NICE. We did it as kids and we can do it as adults.

I hope this article serves you well and shows you how stress drives up your cholesterol, BP and belly fat. I also hope it empowers you to take control of your health.

Prevent Heart Diseases With Healthy Habits

November 1, 2017

Heart Disease Article

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Heart diseases are attenuating the people and among the leading cause of death across the world. The symptoms of a heart attack are not universal to everyone, and certain risk factors make some people more likely to have cardiac diseases. And if we talk about the risk factors associated with it, they are categorised as modifiable and non-modifiable. Risk elements that can be controlled like weight and other habits are modifiable, while risk factors like genetic disorders that can’t be controlled are non-modifiable. So it is quite clear that by choosing healthy habits and lifestyle you can mitigate the heart diseases and can have a healthy heart.

A healthy lifestyle can help you in a great way to control your blood pressure, cholesterol, blood sugar level and stress, which will allow you to prevent heart attack and also dwindle the chances of developing the heart diseases. And it is quite easy to have a healthy lifestyle and can be achieved by adopting some healthy habits like a regular workout, eating healthy food, maintaining body weight consistently, cessation of smoking and usage of other forms of tobacco and restrained use of alcohol.

A regular exercise or workout session primarily contributes towards maintaining a healthy body weight and can keep control over cholesterol and blood pressure. Simple activities like walking your dog for 30 minutes every day, performing some garden work or even cleaning your house are counted as exercise as it will allow you to balance your caloric intake. It should not be intense rather these mild activities if developed as a habit can largely contribute towards achieving a better heart condition.

Your diet can largely contribute towards preventing cardiac diseases. Choosing a healthy meal and snacks option will allow you to avert the heart diseases and its complications. Eating foods that are low in saturated fat and cholesterol can aid in preventing high cholesterol and limited use of salt or sodium in your diet can keep control over your blood pressure level. Your diet should have plenty of fresh vegetables and fruits as they are rich in fibre and can prevent any heart-related problems in an excellent way.

Cigarette smoking and use of any other form of tobacco mainly contributes towards the development of heart pain and other cardiovascular diseases. So for a healthy heart, it is always advisable to quit smoking and use of tobacco. Further excessive consumption of alcohol is also dangerous for your heart as it causes high blood pressure and it should be avoided. People who don’t smoke or have limited alcohol consumption have minimal chances of developing coronary ailments.

Stress leads to loss of sleep, headaches, pain and can even exhaust your body. It affects everyone in one or different ways and chronic stress makes the working of heart difficult. And those who are experiencing stress for over an extended period are more likely to develop heart problems. There are many healthy habits like yoga, regular exercise, having enough sleep, letting off worries by spending time with family and friends that can reduce the stress to a great extent and keep your heart healthy.

Diagnosis of a heart problem has always been frightening, but your healthy lifestyle habits can mostly prevent the chances of developing cardiac diseases. Your healthy habits can better be looked as your strategy to overcome any heart problem.

Stem Cell Therapy & Congenital Heart Disease

November 1, 2017

Heart Disease Article

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In order to understand how stem cells are useful to us, we first need to understand what these cells are. Stem Cells start in the embryo as immature biological cells, then become specialized to create bone, muscle, skin, the heart, the brain, and over 250 other types of specialized cells. This is why they are of such value to scientists doing both basic research in the lab and medical research in the clinic. They have the potential to regenerate tissue and cells that have been lost because of disease or injury.

Stem cell therapy has been used to cure a number of health conditions such as heart diseases, neurodegenerative ailments, and diabetes, with bone-marrow transplant being the most commonly used for this type of therapy. There are many ways in which this cell therapy can be conducted, however, stem cells derived from the umbilical cord blood are the safest to use for treatment. Moreover, these cells from young individuals possess superior naivety and plasticity than those from adults.

Congenital Heart Disease (CHD) is the most commonly found abnormality at birth, where the structure and function of the heart is not normal. In 2014, this congenital anomaly affected more than 1% of live born infants and accounted for more than 2.5 million affected children per year worldwide. CHD now occurs in approximately 7-8 out of 1000 live births, a slight improvement. Recent estimations reveal that up to 80% of newborns and infants with CHD are likely to reach adulthood, which can result in a high likelihood for complications later in life.

The cause of congenital heart disease is usually a combination of genetic and environmental factors. While some congenital heart diseases can be treated with medicine alone, others need to be treated with one or more heart surgeries.

In 2006, research at the Boston Children’s Hospital revealed that the heart has its own source of stem cells. These cells can form two major types of heart cells: myocardial cells (the muscles that, together, contract to make the heart beat) and smooth muscle cells (the lining of the heart’s blood vessels). This finding by Stuart Orkin, MD, and Sean Wu, MD, PhD, gave researchers a better insight in to how the heart forms, and also gave fillip to the concept of treating diseased or defective heart tissue with heart stem cells.

In January 2013, a study led by Bernhard Kuhn at the Boston Children’s Hospital found for the first time that young humans (infants, children and adolescents) are capable of generating new heart muscle cells. These findings gave rise to the possibility that scientists could stimulate production of new cells to repair injured hearts.

A team of researchers from Massachusetts General Hospital reported in PNAS Early Edition (July 2013 issue) that they were able to create blood vessels in laboratory mice using human stem cells. The authors explained that using stem cells to repair or regenerate blood vessels could eventually help treat human patients with cardiovascular and vascular diseases.

Stem cell based strategies to cure heart failure in adults have been investigated with promising results; however, stem cell therapy strategies for the pediatric population with heart failure are in its infancy. Further clinical trial studies will be needed to understand the cell biology in order to optimize their regenerative potential.